Kolhapur: NICS or Non-Invasive Chromosomal Screening a sort of testing of an embryo’s total chromosomal normality previous to being transferred to the affected person’s uterus throughout In Vitro Fertilization (IVF), a technology that’s provided at only a few IVF facilities the world over was efficiently carried out collectively by Lilac Insights, a genetic diagnostic testing firm in collaboration with Patki Hospital.
Elucidating concerning the technology, Dr. Satish Patki, Senior IVF Consultant, Patki Hospital mentioned, “Interestingly five patients have positive pregnancy results after transferring N.I.C.S. tested euploid blastocysts. The remaining N.I.C.S. tested blastocysts are frozen and will be transferred soon”.
He additional added that NICS will enhance chances of pregnancy since solely euploid embryos are transferred and the chances of them being implanted are excessive. It is very helpful for sufferers above 35 years, because the incidence of having an euploid embryos is greater in them. NICS can keep away from switch and subsequent implantation of such an euploid embryos, ensuing in poor pregnancy consequence in the shape of abortions or chromosomal abnormalities in the infants like being born with Down syndrome.
Current follow which detects the chromosomal standing of the blastocyst referred to as Pre-implantation Genetic Testing (PGT) is invasive and traumatic to the embryo and might result in embryo harm. Also, it wants a talented embryologist to carry out the process and high-end instrumentation involving the laser machine.
IVF (In Vitro Fertilization) is an already established therapy for infertile {couples} the place eggs of the lady/ feminine are fertilized with the male’s sperm in a laboratory after which cultured in the incubator. The most mature type of the embryo, in the shape of a ball of a number of cells with a fluid crammed cavity referred to as blastocyst is developed on the fifth day, after retrieval of eggs.
On this main improvement Dr Sam Balu, Head of Genomics, Lilac Insights acknowledged that “NICS in IVF embryos is a game changer. It could be offered as a routine non-invasive screening test for chromosome number for most IVF embryos. A sampling of cells from a single embryo in PGT-A could take up to an hour, sample collection for the test can be completed in a few minutes. The test is a time plus cost saving, non-traumatic and effective method for screening the chromosome numbers in IVF embryos; which is one of the key factors in determining the success of the pregnancy outcome in IVF treatment.”
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